Tricyclic antidepressant with anticholinergic and sedative properties. Amitriptyline hydrochloride appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines. (https://pubchem.ncbi.nlm.nih.gov/compound/11065#section=Top)
"See those hummingbirds?
"I painted those with a silver-tipped paintbrush and an unopened bottle of mint-cream amitriptyline"
- Michael Dickman, "Green migraine", 26 October 2015 The New Yorker (http://www.newyorker.com/magazine/2015/10/26/green-migraine)
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