Tuesday, July 10, 2012

molecules of the day: filipin and amphotericin B

The molecules of the day are filipin:

(PubChem)









and amphotericin B:

 (PubChem)

They're antibiotics that work by associating with cholesterol and thereby altering membrane structure.  (Not clear to me why that would select prokaryotic over eukaryotic cells: any ideas?)

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